Whenever I try running any game with Wine, this window is created and this error is on the Show Details page. I've tested this with several games, all of them error with the same stack.

I've tried 32 and 64-bit Wine prefixes, winXP mode, several games, several Wine versions (w/ Lutris).

Non-games work fine (e.g. wine notepad).

GPU is an R9 380X. No drivers aside from mesa and lib32-mesa. I have the amdgpu.dc=0 kernel parameter set. glxgears draws fine, output of glxinfo here.
OS is Arch Linux.

If anyone could offer an attempt at a solution or anything at all I could try, I would really really appreciate it. I really don't want to dual boot. VFIO is not an option because my CPU doesn't support VT-d.