North and East are the hard flanks they get dreads on 6/8/10 as well as having a few more ships to deal with wave 7 and 9 are bigger than anything South has and probably bigger that everything except wave 10 on west.

I know this is more guide and less build but some people requested it so here it is.

I am assuming you are comfortable soloing south and west thus mostly it is getting in to the right spots.

If you are not comfortable with these flanks go here

Mind Set

The first thing to relies is that it is a easier than you think. Overestimation is one of the biggest causes of failure. that said it is still the hardest content in the game pve wise. Listen to one or more of these they might help calming:

Tirol Concerto For Piano And Orchestra by Philip glass second movement

Pavane by Gabriel fauré (his requiem is really good too)

Concerto for Saxophone by Philip Glass (Quartet Version) mmt 1 mmt 3

Schindler's List Theme by john Williams

Japura River from Aguas de Amazonia by Philip glass

Into The Fray by Marc Streitenfeld from the film the gray (this one was extended by someone)

Sleep by Eric Whitacre

And lastly to get you out of your now very sleepy state:

Reise Reise by Rammstein

Flags by Color of Bubbles

If you really enjoy the works support the artists and buy there stuff. (except maybe fauré he has been dead for 90 years or so)(having met Philip Glass I can tell you he is awesome and deserves it(really good at piano too)(probably too much parentheses)))

Positioning

Make sure you are on the same vertical position and about inline with the middle of your waves to be. Imagine a line between the transport and the bionural launchers you want to be on that line only moving closer or further away from the transport on that line

Acetons can go in so many different plases it is mostly personal preference personaly i put them about 7-9 km away from the transport about 4 km apart (go to 7-9km away make a right go for a bout 2 km drop the aceton put the other 4km away on the other side)

Others put them very near the bionural spawn some people put them above and below the wave there are many ways to do these. North

I honistly can not decide which wave is really harder between north and east. East might technically be harder because it gets more dreads and has a few more ships per wave but on north you really need to be prepared for it.

Wave 1: the first wave is north, it is small and in 2 parts if you have problems with this step I recommend you reconsider going forward.

Wave 2: Nothing here go E or W

Wave 3: small wave go E after north is finished up and help with the dread. Set an aceton if you have them.

Wave 4: another slightly larger wave

Wave 5: Set your aceton if you have them and go help SW or SE there are some bionural torps that come make sure you pay attention so they do not get to the transport

Wave 6:

Part 1

This part is supposed to lull you in to a false sense of security do not let it.

The first group spawns at ~10 km away from the transport you are going to be at 2.5-3km away GW (alpha if you have it) the wave kill it.

Part 2

The dreadnought spawns at (not sure on the exact distance usually more worried about the dread that is .5km away from me) 3.5-4km away from the transport now you use TBR to push the dread to the GW you made for the first group

For those that use Acetons, they only last so long the ones you placed at 3 will probably die just before wave 8 relapse it and use evasive to get back to position.

Wave 7: a some what large group if you only have one copy of GW and no form of CDR only TBR this wave sit at around 5-6km

Wave 8: A lot like wave 6 except more ships and they are not broken up into 2 parts sit at 3km away from the transport TBR immediately as soon as you see the dread and click a target in the further away group to GW proceed to kill the wave.

Your wave 5 aceton is going to die soon due to natural causes replace it so it dose not die at a bad moment. Use evasive to get back to position.

Wave 9: like wave 7 but more ships same strategy applies 5-6km away

Wave 10: Like wave 8 but more ships and the dread is a little further back ~4.5km same strategy as wave 8 but now with romt5 powered GWs. Trigger undine shield regeneration bubble with romT5 for extra shield healing.

East

Positioning is easier than north but you need a stronger ship to deal with the increased number of ships.

Wave 1: go help north you lazy NWS player (unless you are in an atrox or a voquv those are allowed to stay on their flank)

Wave 2: you get something ... 4 ships not a lot

Wave 3: go help north then evasive back to east and TBR the dread back a little. Drop an aceton

Wave 4: once again go north then back to east for a some what small wave.

Wave 5: The exact same thing as West wave 5 first spawns for you are E and SE after a bit A dreadnought spawns. Drop an aceton.

Wave 6: this can be kind of tricky and if you do it wrong a few ships will fly past you with great contempt of your just expired TBR.

Part 1

The dreadnought spawns with a few other ships. Alpha if you have it then, count 4-5 sec(be shooting at them during this time) it is important to count this. after the 5 count TBR them back a little and GW the furthest away ship stay at about 5km away from the transport.

Part 2

A few about 10 sec later(from the dread spawn) right after your TBR turns of if you used it to push the dread immediately another group of ships spawns but because you waited to use TBR your TBR is still active and pushes them in to the GW. Make sure you are still about 5km away from the trasport so the part 2 group dose not spawn on top of or behind you.

REPLACE AN ACETON HERE use evasive to get back to position.

Wave 7: A bit smaller than wave 10 on S TBR them and kill (only GW if you have CDR for GW and can GW at the beginning of the wave)

Wave 8: similar to wave 6 but no 2 part spawn GW a ship in the back group and TBR the dread about 4.8-5km away from the transport.

REPLACE AN ACETON HERE use evasive to get back to position.

Wave 9: this might be bigger than south wave 10 same stratagy as 7

Wave 10: this is a really big wave like really big so big that you might as well be fighting the all of the enemies in gorn minefield enemies at the same time (well at least 2/3 of gorn minefield).

Select something on the back line GW it TBR the dread in to the GW FIRE EVERYTHING if that dose not work inch forward untill you are 2km away and refracting tetryon cascade them(it helps) do not get too close or you will die to warp core breeches DO NOT DO THIS AGAINST ROMULANS.

When you are done go see if other waves need help.

Build Specifics

I am assuming you can solo S/W so your build is not bad. There are some specific build things to go over though.

Aceton is really good at dealing with bionural torps and slowing the waves down GET IT.

NO AFTERSHOCK DOFFS they will kill you by after shocking GWs in to the wrong places(right on top of you). TR after shock doff is fine though if you use TR.

Control builds are really good for those who are willing to work on a little finesse look in to them good ships for it are the Nicor, Vesta, temporal sci, Atrox(hard mode but it can be done), palisade, DSDs in sci mode. These are harder to figure out and pull of initially but those that stick with it will be rewarded with really easy runs(assuming you do the build right).

Captains using ships with SA should get all 3 of the xindi traits and SA the transport so they stack up to full. Switch SA over to the dreads when they spawn though to help kill them. But remember to put SA back on the transport.

Sci captains grab the doff that reduces enemy damage when they are hit by sensor scan it is really good for survivability.

Honestly, if you are here at the point where you can potentially do solo runs of N/E you probably only need to do fine tuning specific to your build not major fixing.