I have been a bedside nurse for 10 years and for the past few months have been working on a cardiac ICU/PCU where I end up maintaining ALOT of amiodarone drips on patients. The cardiologist in this facility will often leave patients on a maintenence infusion for several days and during this time (it seems much more common when the same tubing is used >24 hours) I have noticed that the amiodarone somehow and for some reason begins to vaporize inside the tubing. I can clear the tubing completely of air bubbles and 30 mins to 1 hour come back and there will be lots of small gas bubbles in the tubing.

I am just curious if anyone here has an explanation as to what is going on here. Is this just a property of the amiodarone itself or is it a reaction with the iv tubing? Maybe it's something I am totally missing. Thanks in advance to anyone who cared to read this far hoping someone shares a curiosity in this and can steer me toward an explanation.