Context:

Mark Cuban has opened a new site to buy drugs in the States that has already been discussed a little in this subreddit here.

I wanted to know, if anyone is kind enough to explain:

In Spain in 2010, the cost of an annual treatment of Imatinib was 30.000 € or 45.000 $, which is about 2500 € or 3750$ a month. I don't know how low has gone since then, but it was my understanding it was almost the same. Seeing his website, the retail price of 30 capsules of 400mg (1 month treatment) is cut down from 9000 to 17$. What the hell. This is even cheaper than here in Spain from what I know. And theoretically, we get more fair prices than in the States.

I know pharmaceuticals need high margins to pay for the investigation behind each new drug. But, from my limited knowledge, that's why they got approximately 10 years of the patent and then it was up to the generics free market to make the price more fair to its real costs of production. At least this is what happened with most drugs in Europe.

In Pharmacology classes we learned monoclonals and all the new "specific inhibitors/activators", tinibs, mabs, yada yada, were expensive. A lot. Due to some weird shenanigans of their manufacturing they are the only treatments that once the generic appeared, the price has gone up instead of down. (talking about Europe, I know the States have had historical problems with medical costs inflation).

So, how does this business make prices lower?
Is this some kind of sketchy scam that will blow up?
Or are pharmaceuticals really getting such high profit despite the fact that generic drugs could be cutting the price down so much?
Or is he getting the product from very badly treated labs in third world countries?
Is this the start of a long awaited revolution?

Thank you in advance!

Edit: Now that I am re-reading all that, I still don't really understand what shenanigans make tinibs and mabs so expensive to start with. Sorry for being so clueless.