So I've been wondering this, because I've never taken more than 80mg insufflated, but from people's descriptions of k-holes it sounded like that's exactly what I'm experiencing at the upper end of that dose range...last night I did 65mg and it was way more intense than a tab of acid, I fully lost touch with my body and discrete thought and felt my sense of self dissolve, and I existed as this experience of formless, thoughtless floating/flying energy or sand in the wind. I can't imagine taking twice or even three times that dose, like, my ego was pretty much already dead. Granted I have zero tolerance/only do it a couple of times a year but it still seems like maybe it effects me more than other people?