I personally don’t mind needles so all my use is IM and IV whose bioavailabilities are consistently reported at 93% and 100% respectively.

Rectal administration bioavailability seems to be very under researched compared to other ROA’s but every report I can find consistently records rectal bioavailability at around 25% which is barely higher than oral, about the same as sublingual and significantly less than nasal.

The same sources that report 25% rectal bioavailability give the proper bioavailability we would expect to see from all other ROA’s.

So either they are either somehow all wrong about rectal bioavailability or boofing is actually a bigger waste than nasal administration.

So why do so many people here recommend boofing and even go as far to tell people they are wasting their stuff if they snort instead of boof? All data would indicate the opposite.

The only way that isn’t a waste of half of your drugs is IM and IV administration, however I understand why people want to stay away from the needle. I wouldn’t even recommend going down that route.