I got to thinking about this just now and I like the idea of the original Ghostbusters cartoon one day having a cross over with the New York Ghostbusters. I think a story line they could do is for the two groups to have a legal dispute over who's the true ghost busters but ultimately work together to beat Prime Evil.

Also, I'm curious as to what level Prime Evil would be classified as. I got to figure he'd be a powerful ghost given he's in charge of an entire crew of them. I'd love a serious take on him in a modern comic and I can see the NY Ghostbusters try trapping him only for him destroy their equipment and instead of being trapped the guys just tick him off. Ultimately causing both teams to have to team up.

I saw a picture for the cover of the Ghostbusters: Prime Evil DVD and he looks genuinely scary on the cover that's what got me thinking about it.