So I just read that with Cushing syndrome, you simply can’t burn fat no matter how hard you try. Even if you are in a calorie deficit your body will hold into that fat.

I thought this was fake info but then I searched and found out patients with Cushings can’t burn fat but they burn muscle instead. This is like of the main symptoms of the disease.

How this works y’all? From my understanding, if someone with Cushing consistently stays in a calorie deficit, they will technically lose weight but instead of from fat like they supposed to, they will lose from muscle, but like how is this even possible? Or I misunderstood and they will not lose at all? Because that’s even more crazy.

Regardless how a change in one hormone (cortisol) can cause something significant like that.