I have a question that has been on my mind for a few days now. I apply my estrogel always in the armpit five times a day. It's a place that experiences the least contact with my clothing, is moist, easily reacheable and reduces contamination via my hands.

As far as I learned repetitive applycation results in higher concentration and thus a better absorption rate. Diffrent skin areas absorb stuff better than others based on fat tissue, blood vessels and skin thickness. Areas such as crotch, armpits and beneath / around the chin are to favor. The skin in these areas differ greately and every person is diffrent but here goes: Is there a rough general number how much the skin can absorb per square unit? How much is the effective amount to be used, so I don't apply excess estrogen / or have to change areas?