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Three creatine supplementation studies
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Six-Week Supplementation with Creatine in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Magnetic Resonance Spectroscopy Feasibility Study at 3 Tesla

https://www.mdpi.com/2072-6643/16/19/3308

Eight-Week Creatine-Glucose Supplementation Alleviates Clinical Features of Long COVID

https://pubmed.ncbi.nlm.nih.gov/38684388/

Effects of six‐month creatine supplementation on patient‐ and clinician‐reported outcomes, and tissue creatine levels in patients with post‐COVID ‐19 fatigue syndrome

https://www.researchgate.net/publication/374072547_Effects_of_six-month_creatine_supplementation_on_patient-_and_clinician-reported_outcomes_and_tissue_creatine_levels_in_patients_with_post-COVID_-19_fatigue_syndrome


Also, anecdotally, I have been taking 5 g/day for two weeks and feel like I've noticed improvements to focus, short-term memory, and physical energy. But it's subtle and I can't prove it's the creatine.

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