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Purification of N-benzylbenzamides
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Working on some amide functionalization reactions but I am having a problem with the purification. H-NMR internal standard shows around 89% yield but I am recovering less than 50%. The starting benzamide is used in excess and is poorly soluble in the eluents that I am using for the column. Any suggestions for purifying secondary amides that I can try?

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3 years ago