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Major improvement from SSRIs - now I’m confused
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Hello fellow warriors

Just some background. In 2020 I started experiencing severe dizziness, lightheadedness and drowsiness following a period of infection and stomach pains. At first, fatigue wasn’t a major symptom, but I did experience some crashes. I developed anxiety and depression due to the horrible experience of being unwell and having no idea what was going on. The fatigue mostly came later and became a major symptom following a period of severe stress. A GP diagnosed me with Chronic Fatigue Syndrome, anxiety and depression in 2021.

Recently I started SSRIs (antidepressants) to treat my depression and anxiety, however the psychiatrist did say it would help fatigue. Now, my fatigue has decreased substantially. A month ago, I was 95% housebound and a trip to the doctor would put me out for days. Now, I’m able to go out for lunches, do chores, go for walks ect.

So now I’m a bit confused. I wouldn’t expect SSRIs to cause such a major reduction in fatigue for an ME/CFS patient. So now I’m thinking: a) I didn’t have ME/CFS at all, but have POTs which causes some fatigue, then the fatigue became substantially worse from depression. b) I have mild ME/CFS and the depression added a lot more fatigue, so now that I am treating the depression I am back to a level of fatigue consistent with mild ME/CFS c) I had post-viral fatigue which was worsened by anxiety and depression.

Thoughts?

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1 year ago