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Extravasation: IV chemo leaked?
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Has anyone dealt with this? I read it’s rare, but I had my 3rd treatment of Docetaxel and Cyclophosphamide (TC) last Wednesday. I didn’t notice any leakage at the time of infusion, but thinking back the IV did hurt a little more than usual.

Over the past few days, I’ve developed a couple (what appear to be) small red blisters at the IV site. I just call my oncologist and got the PA, who (very annoyingly and frustratingly) didn’t seem too concerned. She said extravasation was rare and she has never seen it in person, but she’d chat with some colleagues tomorrow and show them the pictures I sent her. She seemed to be leaning more towards infection but my skin in literally burning (not hot to the touch) and the blisters, while still small, have slowly gotten worse over the past few days.

I’ve been reading some scientific journals on Docetaxel extravasation and how delayed it can be in showing up. The timeline, redness, blisters, and pain all track and it’s just too coincidental that it’s at the IV site. I know I’m not a medical professional but this seems pretty clear to me.

I’m obviously nervous, and annoyed at the dismissal of the PA. If I do have this, treating it asap with steroids seems to be the recommended course of action so it doesn’t get worse. I shouldn’t have, but googled some nasty looking pics.

Anyone have experience with this chemo complication?

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Thank you so much! I read Docetaxel is classified as an irritant but can rarely present as a vesicant as well…so that just adds to my worries. Waiting on a call from a nurse today. It didn’t get worse overnight so it’s still pretty mild…I’m just worried it will get worse over the weekend.

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Wow I’m so sorry you went through that, it did sound like absolute hell. Just add it to the joys of having and treating cancer 🙃 mine is still looking pretty mild this morning but I had a full meltdown last night just because it’s one more thing to add to the plate.

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Hearing your friend had a similar experience makes me feel less alone, so thank you for sharing! I only have one more treatment left but I will ask about a dermatologist specializing in oncology…appreciate it ☺️

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Thank you so much for the response! I felt like a crazy person for a minute so this is validating. I only have one more round of TC left, it’s in a couple weeks. Mine seems pretty mild, I’m just nervous it’ll get worse. Two blisters, the bigger one is probably 5mm. Did you not treat it the first time it happened? Did they continue to get worse with time? Definitely feels like a chemical burn!

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4 months ago