First I am not going to suggest my wife’s(45f) depression anxiety ptsd and SI are just bad PMS

Wife is currently in a residential treatment for all of the above. During her intake her doctor made an initial diagnosis of bipolar 2 and after a not good few days on Latuda(sp?) switched her to lamictal and started the ramp up with that. However I have been asking for a while for her hormones to be checked. We have been married for 25 years. Irregular to insane periods have been the norm for her entire life to the point when we had our last child 8 years ago she had a partial hysterectomy to be done with other. Retained her ovaries but uterus removed.

Fast forward to the last three years which have been a steady downward spiral of anxiety and depression. She was assaulted when she was younger and is working on ptsd with her her counselors but it’s been slow progrsss with it while the anxiety and other challenges have gotten worse. She has been drinking heavily (getting treatment for that as well). Anyway at the residential facility I asked her doctor to check hormones since it was a problem in her life for so long and there is no way obviously to tell how it’s going with no periods. Well she is 1042 for estrogen and upper limit of normal even at highest durinovulation is -350. So now we are both wondering is she bipolar or just big swings with serious estrogen dominance or both?

TLDR anyone initially treating bipolar only to learn the main issue was estrogen dominance?