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Do I need to downsample for DEG etc. analysis - Seurat ?
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Hi,
So I am relatively new to Seurat and single cell analysis.
I am wondering if I have two populations, say one with 1000 cells the other 10000, and if so when I do analysis such as differential gene expression and Gene Set Enrichment Analysis, whether I need to downsample the 10000 group to close to 1000 ?
if yes then why ?
Thanks!
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