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can u deduce the background info from a given single cell (Seq) ?
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it's like Sherlock Holmes's theory, "show me a drop of water and i would be able to deduce which lake, river or sea it comes from"

suppose you are doing scRNA-seq, and all the annotations and labellings etc are masked, would you be able to deduce those info just based on purely the scRNA-seq transcriptomic data from that single cell ?

like gender, organ origin, etc. ?

thanks

ps: i think the short answer is def yes, but i suppose it's not that robust ? as to me it's always based on clustering, or at a "population" level that we define this or that cells are this or that ?

thanks!

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1 year ago