In classical physics if you have a reaction chain a -> b -> c where a has more energy than c but a -> b requires more energy than b-> c gives it is possible to have a catalyst on the a->b step that will lower that transition energy enough that the end result is exothermic.

My question revolves around the Uncertainty principle as a catalyst. So long as the decay steps are very quick is it possible to borrow enough energy for a->b that you give back from the excess energy in b->c? You would have to hyperlocalize the particle so it's energy state gets very uncertain but at least logically this makes sense to me. As I'm still a student when it comes to Physics I'd like some of the more knowledgeable people here poke holes in my hypothesis for me.