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Why does Gabapentin work and feel differently for me than Pregabalin?
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I know theyre pretty much identical and are both gabapentinoids that work as VGCC, and i know that Pregab is like 6x stronger, but why does Gabapentin feel different for me than Pregabalin?

My tolerance for Pregabalin is EXTREMELY high, and i would need ALOT to feel it. and it feels like a stimulating euphoric high.

But Gabapentin on the other hand, for me, I would only need to stagger like up to 4000mg to feel it, and it just feels different, more like a weed high, where my eyes get comfortable and I just feel relaxed and mood lift.

My pregabalin tolerance is at like 6000mg, which is wayyyyyy more than that 4000mg of Gabapentin when you compare the ratio considering that its 6x stronger.

Can someone please explain to me why its like that for me?

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2 months ago