Ethchlorvynol (Placidyl) potentially easy synth?

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So while researching old school sedatives, I read that a lot of people miss (and/or really want to get ahold of) ethchlorvynol. I thought I’d search the synthesis, and found this:

“Ethchlorvynol, 1-chloro-3-ethyl-1-penten-4-in-3-ol (4.3. 3), is synthesized by the condensation of acetylene with 1-chloro-1-penten-3-one in liquid ammonia [34,35]”

Is it just me or does this seem pretty feasible?

Source: https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/ethchlorvynol#:~:text=Ethchlorvynol, 1-chloro-3,ammonia [34,35].

Comments

SunderedValley

👀🤨

Dead simple sedatives might legit fill a niche.

At some point the RC/Bulk alp well will run dry and then a lot of rec users are boooneeed.

Good find.

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SunderedValley

PS. I am currently devising a new GBL/GHB synthesis that shouldn't involve nitration/sodium nitrite, nitrosamines, any of that nasty bullshit. The procedure is accessible for most labs, and the reagents kinda easy to access.

This is turbo relevant.

Now that its rare, and has the endorsement of Macafee, suddenly people regad MDPV as a legendary substance? Hard disagree, i say. But the perception persists....

That's a pretty good example, aye. IMHO if you want that "yep, I'm basically re-enacting a black and white film about the dangers of weed" feeling a-pvp is really more appropriate but people get fixated on the darnedest things.

Unfortunately this compound has many of the same traits that make it dangerous /otherwise incompatible with the contemporary bartards, same as GHB & Barbituates:

I'm not looking for non-problematic so much as simply available and clean, but good points.

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