I've been bioassaying OCS edible product and can't help but notice massive variation in the effects. I dose in the morning, so I have an empty stomach and I'm starting on baseline. Today I tried an Indica Capsules product, which claims 7.4 mg THC per cap. I took 5 caps, so 37 mg THC total. I felt nothing. With other products I've taken 30 mg THC and it's been almost too much!

The pharmacology of cannabis products is much more complicated than what is reflected by simple THC/CBD measurements. We do not understand the pharmacology very well. Pretending that we fully understand the pharmacology and that simple THC content measurement is the determining factor of the subjective of effects on the user is dangerous because it sets the user up for potential unintentional overdoses. If a new user to edibles calibrated themselves off of these Indica Capsules , they might determine that they had a tolerance of several hundred milligrams. In fact that would be a very uncomfortable overdose for them which could end up leaving them in a hazardous situation.

Each of these edible products should be bio-assayed by experienced drug users and rated at various doses using the Shulgin Rating Scale. This would be of much more benefit to most users approaching a new product for the first time, especially since THC measurements are practically meaningless and potentially dangerously misleading.