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Berberine
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Recently found out about existence of this strange molecule, seems to work great for adderall/stims side effects overall. Also kills the high real good. It is natural alkaloid which is A2 agonist and dopamine antagonist due to mirrored classic stimulant structure, it is also very similar to MDMA in a way but is not that strong, studies suggest serotonin transporter modulation and raising serotonin and dopamine levels overtime. Also it is NMDA antagonist although weak one. A2 agonism is really useful there as well as dopamine antagonist activity which both can kill stim and overamp. It is vasodilator also. Do you have any experience with it? Works really well to get some sleep, never used tizanidine after getting berberine. There is a study where it helped meth addicted rats with withdrawal. Still please be careful out there 🙏

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1 week ago