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Iā€™m posting my experience with some unfortunate side effects I have had with sprinolactone.

Iā€™ve been on spiro for almost two years now, going up to a dose of 200 and I can safely say itā€™s caused my face to age. I donā€™t know if itā€™s actually aged, or just dehydrated and appearing more aged but my smile lines have suddenly become more pronounced and the most obvious part is my lips have gotten much smaller and thinned out. Luckily my lips were full to begin with so itā€™s not too noticeable but it is to me- and I know itā€™s not in my head because I have compared pictures, find myself pouting slightly more in pics and unable to get same result, applying lip liner more often- they were never an insecurity for me so it is really a shame . And all for nothing because it didnā€™t even help my hair.

I have found a couple other posts on reddit also noticing sides similar to these and the two main theories seem to be that this is caused by spiro impacting collagen production OR spiro causing dehydration. I literally take collagen every morning but this has still happened. I could drink more water though but I still drink over a litre a day.

I really hope these changes arenā€™t permanent and my skin will plump up again once I am off spiro. I m am slowly weaning off it, I honestly just want to stop it but I am so concerned about hair loss from the shock of stopping so doing -25mg every month.

This is not to fear monger, and I know some people have had excellent results with spiro. But this isnā€™t the first complaint of this sort Iā€™ve seen and I would like to add my experience as I thought I was going crazy and there are not many validating posts about this on the internet. So to anyone who thinks theyā€™ve noticed the same- no youā€™re not crazy

Does anyone have any idea if my lips will go back to normal once I am off spiro?

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Interesting!! Had no idea..

you have to wean off it?

i've gone "cold turkey" a billion times.. I wasn't aware you were supposed to wean off it.

and I've only noticed it can be drying >> your face gets more bleh IF you don't stay hydrated.. for me personally.

unsure on collagen production... you could always pair it with a packed vitamin.. I do a pre-natal vitamin with it.

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8 months ago