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Aripiprazole as an adjunct to other dopamine antagonists?
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Seen this a few times recently in clinical practice but can’t find much in the literature.
Using a high affinity partial D2 agonist alongside D2 antagonists doesn’t make sense to me. Surely it would just decrease the effectiveness of the D2 antagonist by using up/blocking the D2 receptors?
I understand using it in low dose to reduce prolactin levels but not as an adjunct for psychosis treatment.
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