I’m looking to see if anyone else has experienced this.

This is my second round using CJC/Ipamorelin. I’m doing Monday to Friday injections, first thing in the morning and again before bed, both times fasted.

The first time I used these peptides, I had zero issues and felt like they worked great. However, after taking a few months off and starting again, things aren’t going as smoothly.

Now, after my morning injections, I almost always break out in hives around my stomach. I’ve tried switching injection sites, lowering my dosage, using new vials of both peptides, and even trying a fresh batch of bacteriostatic water—but the hives keep happening.

Sometimes I’ll also get flushed (which I think is normal), but it’s the hives that are really getting old.

I’m wondering if anyone else has experienced this or found a solution? Did your body just start reacting differently over time?

Any insights or advice would be greatly appreciated!