Research Subject (RS): A 41-year-old male who has successfully lost approximately 130 pounds and is on a journey to achieve further weight loss. RS initially lost 50 pounds through diet alone and an additional 70 pounds with the aid of semaglutide. However, weight loss has plateaued, and RS’s insurance no longer covers semaglutide. With a BMI still around 30 and about 70 pounds left to reach their goal, RS has decided to begin using retatrutide.

Question: RS is exploring whether other peptides could support fat loss during this phase of their journey. They are concerned that many peptides may be less effective until body fat levels are significantly lower and closer to goal weight. RS has faced long-standing struggles with weight and seeks to maximize their chances of success.

Details for Context: • Retatrutide has been chosen due to its promising effects on weight loss. • RS is open to additional peptide options or strategies that could enhance fat loss alongside retatrutide. • RS seeks evidence-based suggestions or personal experiences regarding the efficacy of various peptides, particularly at a BMI of 30 or higher.

Key Focus: Are there peptides that are effective for fat loss at this stage of RS’s journey? Or is it true that most options are more effective closer to goal weight? RS welcomes any insight, guidance, or relevant experiences to help navigate the next steps.

RS’s Goal: To optimize their strategy and achieve lasting success in reaching their target weight.