Sorry to sound gross. For breakfast I ate a pint of Halo ice cream (so good!) and had diarrhea after. Even after taking my rx'd pain pill, I still had it and reluctantly took Imodium which is still kind of an opioid. And zinc, which helps with diarrhea too yet the zinc can lessen the presence of coke, amphetamines, and THC. I don't think it would affect anything else. Some studies say Immodium may show up on a drug test, others say no, and others say if you abuse it. In a couple of hours I have to see my pain management doctor and in the event they randomly test me, should I just say that I had to take the Imodium this morning to come to the appointment? What's the worst that can happen, I ask to be retested in a day or two? I'm in the US and my pain contract says that I can't take illicit drugs or get Rx'd other pain med from another doctor unless it's an emergency. Immodium is over the counter and you don't even need to be 18 to get it. Very popular and effective medicine. I also really want my trigger point injections today.