Hello, 31F here. I’m sorry for the long post in advance, I’m really desperate and need some advice because my life is hell right now. I’ve been having PVCs since 2018. After the initial tests (24h holter, ultrasound and stress test) I was given the lowest dose of nebivolol and told that it’s normal and to just learn how to live with them. And that’s what I did, for the next 3 years (I stopped the beta blocker after a month). Even though their number kept on increasing (first holter found 100, the one in 2020 found 3400), I got used to the pattern - they’d only show up at night before sleep and morning after waking up, often related to my period. It was annoying, but I was living my life normally. Fast forward to April 2020, when I woke up one night with heart rate 160, shaking, numb tongue and lightheaded. It calmed down to 100 after few min, at which point I was shaking out of pure panic for the next hour. After a month, it happened again, so I went to see my doctor, who prescribed me omeprazole and bisoprolol. It didn’t help, and once a month I kept on getting these night tachycardias. Trips to the ER were useless because by the time I got there, it went down to 120bpm and just showed sinus tachycardia. Finally, my cardiologist put me on propranolol. I was taking 20mg 3x per day, and even though I was still occasionally getting tachycardias, it was very rarely and it would jump to 100-120bpm which was bearable. On the other hand, number of my PVCs was slowly but steadily increasing, still manageable though. Then, in December 2021, it all took a 180 degree turn and it’s been getting worse ever since.

During my annual cardiologist checkup, he decided to switch my meds and try with propafenone, and it was a disaster. My PVCs went wild, my tachycardia came back, this time during the day and 160bpm, again. PVCs were in constant bigeminy and trigeminy, which before, even if I got a couple of flares, it was for a few sec and I didn’t even notice, but this time it was non stop for few minutes at a time, and more importantly, it started happening during the day, while I was up and about. Then the cardiologist switched me to metoprolol 50mg and things didn’t improve much. Since then, I’ve been still getting night tachycardias with various length and intensity (after 2 years no one still knows why this is happening, although I have my suspicions because it happens either in the middle or beginning of my menstrual cycle), and my PVCs are still all over the place. Now they happen mostly during the day, every time I’m walking or doing something standing up.

Now, 2 months ago it got worse again, some days feeling like every 3-5 beats were PVC, trigeminy was back and my life just stopped. I’m constantly dizzy and with every extra beat I feel uncomfortable, sometimes painful squeezing around my heart, I’m scared to go out or even move, especially if I’m alone. I have to mention that 3 months ago I started a nose spray that is a combo of corticosteroids and antihistamines, which are known to make arrhythmia worse - I stopped using it 2 weeks ago. Two weeks ago I did a 72h holter and luckily I wore it on the worst day I had so far, but the results put me in a state of constant panic and I’m scared to even leave the bed. Even though the burden is pretty low, it caught 2x NSVT (it was 4 beats and at hr <100) which I didn’t even feel, and during those trigeminy/couplets runs I was feeling awful, dizzy, tightness of chest with every extra beat. But worst of all, and the thing that’s giving me nightmares and keeping me in the house since I got the results is the long QTc. The doctor didn’t even mention it in the written report, and the paper shows that the longest was 522ms, which should be very worrying. I went to check my other holter results, as well as the stress test, and none had QT interval even mentioned. Among the countless ecgs that I did over the years, the ones that mention the interval always show QTc <400.

These are the results of the 3 days holter.

I guess my question, for anyone who was going through a similar thing, just to get a little peace of mind until I can see my cardiologist in a month:

Is it possible that this computer generated report calculated the QT interval wrong?

Can a cardiologist suspect the long QT just by looking at the ecg report?

Can the lqts go undetected for so long and after I did 6 holters, 2 echos, 100s of ecgs and a stress test?

Did anyone else have their PVCs completely change their behavior in the past year? Could it be connected to the covid vaccine? (I was asked at the ER once if I noticed the symptoms worsening after the vaccine, so I guess they’re suspecting something. I’m vaccinated 3 times but the problems started happening 5 months after the second dose)

Anyone has any experience with night tachycardia after suddenly waking up? I can wake up 29 days in a month from a nightmare and my heart doesn’t even flinch.

I apologize once again for the long post, my quality of life atm is 0 and I was hoping to get some advice from people who are going through the same thing as me. My cardiologist just keeps on repeating that my heart is healthy, that he doesn’t know why I’m getting the night tachycardias and why my PVCs changed this much and that’s it, I’m not getting any further explanations. I have another stress test scheduled in 2 weeks. I tried taking different kinds of magnesium, except for magnesium taurate because I live in a small country and it’s not available here - didn’t help. I’m taking alprazolam or diazepam when needed, but lately I need them all day every day to function. Thank you once again for reading.

TL;DR : PVCs getting progressively worse since December, changed their behavior from in rest to while up and about, lots of trigeminy, latest holter shows nsvt and lqt which put me in constant state of panic.