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Help with understanding SNPs
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This is what I understand, SNPs are single letter substitutions in the genome. They are identified by a registered number that you can look up in the SNP database, and it will give you a chromosome/offset for the location of that letter.

What I don't understand is, how does this account for variations of genome length due to insertions/deletions? It seems to be an absolute offset into the chromosome, so say somebody has a mutation of 1000 letters that got inserted/deleted, none of the offsets for SNPs after that mutation would have any useful data.

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1 year ago