From https://www.accesswire.com/839246/fsd-pharma-presents-positive-results-on-first-in-human-phase-1-study-of-lucid-21-302-lucid-ms-at-americas-committee-for-treatment-and-research-in-multiple-sclerosis-actrims-2024-forum

TORONTO, ON / ACCESSWIRE / March 5, 2024 / FSD Pharma Inc. (NASDAQ:HUGE)(CSE:HUGE)(FRA:0K9A) ("FSD Pharma" or the "Company"), a biopharmaceutical company dedicated to building a portfolio of innovative assets and biotech solutions, today announced its participation in Americas Committee for Treatment and Research in Multiple Sclerosis ("ACTRIMS") 2024 Forum held during Feb. 29 - Mar 2, 2024, in West Palm Beach, Florida. ACTRIMS was founded in 1995 and is comprised exclusively of Multiple Sclerosis ("MS") researchers, clinicians and key stakeholders. The annual conference is the largest of its kind in North America in MS.

Represented by senior Research and Clinical development team and co-authored by several of its esteemed scientific advisors, the Company shared the results of Phase-1 clinical study in a poster presentation, "Lucid-21-302 (Lucid-MS) for Protecting Myelin and Neurons and Preventing Disease Progression in Multiple Sclerosis: First-In-Human Phase-1 Dose Escalation Study in Healthy Volunteers". This presentation detailed the final results including adverse events profile of Lucid-21-302 in the single-ascending dose (SAD) studies. The study concluded that Lucid-21-302 is safe and well-tolerated in the dose range of 50-300 mg p.o. administered once, with no difference in pharmacokinetics between the fed and fasted states. There were no SAEs, and most AEs (7/12) in participants receiving Lucid-21-302 were characterized as unlikely related or unrelated to study drug. In the dose range 50-300 mg, drug exposure was proportional to dose of the drug. It also demonstrated good oral absorption with AUC at 300mg comparable to AUC in mouse efficacy studies.

Lucid-21-302 is a first-in-class, non-immunomodulatory, neuroprotective compound with a unique mechanism of action for the treatment of MS. It is a patented New Chemical Entity that has shown in preclinical models to prevent demyelination, a known cause of MS and other neurogenerative diseases characterized by damage to the myelin sheath surrounding nerve fibers in the central nervous system.

The presentation was during the Poster Session 1 of ACTRIMS from 6:00 PM to 7:30 PM (EST) on February 29, 2024. The presentation is available on the FSD Pharma website under the "For Investors" tab following ACTRIMS 2024 Forum.

"This was a great opportunity to share our latest and positive results with the global multiple sclerosis community. We look forward to continue the clinical development of this asset to advance ground breaking therapies for the treatment of multiple sclerosis," said Dr. Andrzej Chruscinski, Vice President for Scientific and Clinical Affairs, FSD Pharma.