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Thought I'd let people know my experience using mephedrone and MDMA (both serotonin releasing drugs) in the days following either DXM or methamphetamine use. Meth and DXM seem to block the effects of MDMA and mephedrone, as if they are acting like an SSRI (which we know blocks MDMAs effects). Both meth and DXM are known to have serotonin reuptake inhibition effects, albeit presumably to a lesser degree than depression SSRIs.
Maybe this doesn't happen for everyone, but apparently for me it does. MDMA and mephedrone don't work for a couple days following DXM and meth. So if you had a bad roll a couple days after DXM or meth use, there mightve been a good reason.
Happy rolling!
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