Introduction

MDMA, short for 3,4-Methylenedioxy-N-methylamphetamine, is an entactogen with stimulating and hallucinogenic effects. It was first synthesized in 1912, but more widespread use not being of any true relevance until the late 1960ss/early 1970's. MDMA is an interesting compound in that it is stimulating, but has much different effects on the mind and body than traditional stimulants. It is also reported to have many psychedelic effects, but again, very different from traditional psychedelics such as LSD or psilocybin. As I mentioned above, it is labeled as an entactogen, not a stimulant or psychedelic.

Dosage, tolerance, interactions etc.

SCALE

• Very light: 40 - 60 milligrams

• Light: 60 -100 milligrams

• Moderate: 100 - 135 milligrams

• Strong: 135 - 170 milligrams

• Very strong: 170 - 200 milligrams (Never exceed 250 MG)

(Recommended dosage can vary by body weight, personal experience, health and more)

FIRST EXPERIENCE

For a first timer, depending on desired intensity, your body-weight and personal drug experience you will probably want to dose somewhere in between the light and mild dose ranges. Very light may be good for someone with little to no prior experience with MDMA or other compounds, but asides for that anything above those ranges isn't wise for a first experience.

HOW OFTEN CAN I ROLL?

At most, it's pretty universally accepted that you should not be dosing more than once every three months. Although it is hard to exactly say, we do know for certain that taking excessive dosages and or abusing in the long term is neurotoxic. MDMA highly serotonergic, and should be respected.

TOLERANCE

Tolerance should not be a worry with MDMA, as I mentioned above you should not be using it anywhere nesr often enough for this question to rise. MDMA is not a sustainable drug to abuse, by any means. It's literally a situation where you are better off taking something else.

JUMP IN DOSAGE

Reasonable jumps in dosage can range from 25-50 milligrams, although you really shouldn't be exceeding 200 milligrams at an absolute most 250. MDMA is not like psychedelics where you can take multiple times the needed amount and its physically safe... MDMA is absolutely a compound where harm reduction guidelines need to be strictly followed.

RE-DOSING

Re-dosing is never a smart option, but if you do wind up re-dosing make sure it's only one re-dose and prefeably prior to three mayhe three and a half hours in. Also, keep your starting dosage in mind. Re-doses realistically shouldn't exceed 50 milligrams, and your total dosage should never exceed 250 milligrams. (Including your re-dose)

HOW TO AVOID BAD COMEDOWNS

Avoiding bad come downs all comes down to smart planning, pun intended. Using the basic understanding of MDMA pharmacological, it's pretty easy to pinpoint what causes it and ways it can be avoid. Firstly, excessive dosage. Exceeding 150 milligrams in this regard is not wise. Second, make sure you are well rested, properly hydrated and have eaten properly the days leading into an experience. It really has to do with self-care, precise dosing and better decision making.

Harm reduction, testing, set & setting and more

MDMA is a relatively safe compound if you follow harm reduction protocol. I will go over a few key points down below, all being equally important in their own way. Like I previously stated, MDMA is a compound where you need to strictly follow harm reduction practices. Not just one or the other. MDMA is similar to psychedelics in the fact that the way you approach things will have a great impact on your time spent on the substance.

REAGENT TESTING

Reagent testing is a must no matter what you are consuming, I can't think of a single valid excuse to not be testing. Research chemicals and Fentanyl prevalence is at an all-time high, and only climbing by the day. Check out r/ReagentTesting.

MEASURING DOSAGE

To do this, you will need a scale. In one gram, there is 1,000 milligrams. If your scale measures in milligrams, this will be easy. If its not as accurate and can only measure by the "point" (100 milligrams), you will need to be extra careful. Pretty much, you need an accurate scale. There is no tips/tricks that work, trust me. If you don't trust your scale, buy a new one. Identifying the dosage in pill formed is not possible.

HYDRATION

MDMA is a compound that can dehydrate you at very considerable levels, much more than even most traditional stims if not all. You have to make sure you are drinking enough, but don't drink to much. That can be just as bad as to much. It would be smartest to have both a minimum, and maximum, amount of good hydration ready before dosing.

BODY TEMPATURE

Temperature control is a must-have with MDMA in my opinion, this is a huge drawback when it comes to festivals, concerts etc. And we all know MDMA is notorious for being the drug of choice in these settings. This is probably the hardest one to control, but always keep this in mind as well. Having something you can check your body temperature with just in case never hurts.

DANGEROUS INTERACTIONS

• Avoid:

[Some of these are very good examples of why you should always do your research before combining drugs, or taking even a single drug for that matter]

Other serotonergic compounds (serotonin syndrome)

DXM (serotonin syndrome)

Tramadol (serotonin syndrome/seizures)

MAOI's (serotonin syndrome)

5-htp (serotonin syndrome)

NBOMe's (Cardiovascular risk/overdose risk/other)

Stimulant drugs (Cardiovascular overload/increased neurotoxicity)

• High risk:

[Any combination can be risky, especially some off these, and the reality is most of these are actually very common - do your research and follow harm reduction protocol!]

Opioids (Overdose potential)

Alcohol (Over consumption)

Benzodiazepines (Blackouts/other)

Psychedelics (Physically safe, potentiation factor)

Most dissociatives (Physically safe, potentiation factor)

Most depressants (Over consumption/overdose potential)

Diphenhydramine/Deliriants (Work on serotonin and very dangerous)

NO INTERACTION

• Physically safe

[Even "physically safe" combinations carry their own risks, make sure you adjust your dosages and do your homework on what to expect]

Cannabis

Psychedelics

Dissociatives

Kratom

Nicotine

Some hallucinogens

• No interaction but not recommended/risk factor:

[While it is true these drugs have no interaction, combining them with MDMA does carry a set of risk, some more than others - Not advisable]

Opioids (Overdose risk)

Alcohol (Over consumption/further dehydration)

GHB (Over consumption can lead to respiratory depression)

Benzodiazepines (Blackout potential)

Caffeine (More stress on your cardiovascular system/anxiety)

THINGS TO AVOID

It's best to treat MDMA in a similar fashion to psychedelics. Dose in trusted places, around trusted people with as good of mindset as possible. Avoid all potentially risky situations, MDMA is not a compound that leaves most users as prone to negative experiences as say psychedelics; but it is by no means impossible. If you are are not experienced with MDMA, I wouldn't advise throwing other drugs in the mix.

MDMA VS XTC, MOLLY ETC.

Xtc is usually referring to pill form MDMA, while molly is usually referring to the pure crystal product. People throw these phrases around every chance they get. The only thing you need to know is XTC, Molly, etc. are all just different names for possibly different forms of MDMA. What you need is a reagent test kit, these names tell you nothing. Pills are cut much more often thab pure product, keep this is mind.

A BRIEF LOOK INTO MDMA's HISTORY, CULTURE AND THERAPEUTIC VALUE

HISTORY

MDMA has quite interesting history, much more than I am going to get into today. As I mentioned above, MDMA was first synthesized in 1912, but didn't see any recognized widespread use until the late 1960s to early 1970s. MDMA was actually synthesized originally in hopes of a compound to treat excessive bleeding, little did the man who synthesized it know he had created a compound that would be recognized on a global level in just a few decades.

According to the available information, Alexander Shulgin it's one of the first to have experimented with MDMA on any considerable level. After having tried the substance, Shulgen strongly believed the substance couls have great potential therapeutic value. He actually started advertising it to therapist and psychiatrists, which inevitably led to a gain in popularity. This what most consider to be the start of MDMAs path to global recognition. Alexander Shulgin is an absolute legend, psychedelic pioneer, check him out some time.

CULTURE

MDMA was always closely associated with psychedelics, cannabis and other hallucinogenic compounds. The peak of MDMA's historical values definitely towards the later 1960s to mid 1970s, with many of the most popular names in music and other lines of entertainment having done or even directly referenced it. You could certainly say played a big role in the Psychedelic era we all know and love. It was actually known as the "love drug" during this time.

MDMA has been shown on a lot of love, but as any other drug has is received it's fair share of undeserved judgment. It did wind up catching attention of the drug enforcement. After many hearings, a US federal administrative law judge recommended MDMA should be a schedule 3 drug. Basically meaning it does have potential for recreational abuse, but also has at least some medicinal value. Despite this, the director of the DEA overruled this recommendation and labeled it a schedule 1 drug. Basically meaning it has potential for abuse, but no recognized medicinal value.

THERAPEUTIC POTENTIAL

We have long known about MDMA's medicinal values, this goes as far back as the late 1960s. As soon as psychedelics, cannabis, MDMA, other hallucinogens and pretty much all other recreational drugs as a whole became "scheduled" all legally funded and performed research pretty much came to halt. Up until the last 10 or so years, there was no research. None. One of the first large scale (MDMA based) studies was performed around the times of ~1967-1970 by Dr. Leo Zeff and to say the very least they were shocking and promising. Over 4,000 participants.

MDMA has been proven to be effective in treating countless different disorders and mental health issues! Such as depressive disorders, PTSD, anxiety-based disorders and even drug/alcohol addiction. I could name so many more, it's truly astonishing what all one compound can target. There is hope! Psychedelics, MDMA and even other recreational drugs are being decriminalized all over the United States and other parts of the world. Research is at an all-time high, medicinal access is at an all-time high, and most importantly, harm reductionis at an all-time high. Change is possible.

Outro and community feedback

This is just a brief summary of things one should know prior to experimenting with MDMA, I did my best to keep it short but deliver the information you need. If anyone has any suggestions on things I should/edit/other, please let me know down below! Feedback is always appreciated, makes things like these easier. I tend to over think the small details, LOL! I may add to/edit this over time, who knows. Buy as always, best wishes to everyone out there reading. I hope this helps someone and happy rolling! Much love! ❤

~ RoBoInSlowMo