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As I understand it, you need breaks between rolls to let your body build your serotonin back up. First off, is that break needed to restore serotonin AND because of receptor down-regulation or is it ONLY because you dumped so much, it got broken down and you need to make a new supply?
So, I hear so much about needing to rebuild your serotonin supply, but not much about dopamine and norepinephrine, which both are released/uptake inhibited like serotonin giving the famous entactogenic/stimulated effect of MDMA. Do we not hear as much about those because they have less down-regulation and/or are built back up faster?
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