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Muscimol and Nardil
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Muscimol, a constituent of the mushroom Amanita muscaria, has very potent agonist activity at GABAARs. It is a more potent agonist at GABAC receptors than at GABAA receptors Moreover, muscimol inhibits neuronal and glial GABA uptake, and it is a substrate for the GABA-metabolizing enzyme, GABA transaminase (Krogsgaard-Larsen, Falch, & Hjeds, 1985; Krogsgaard-Larsen, Hjeds, Falch, Jørgensen, & Nielsen, 1988). Nardil is an irreversible inhibitor of GABA transaminase

I am currently taking 45 mg Nardil and also took 2g of Amanita muscaria fully converted to Muscimol. Mild relaxation was observed after 40 mins typical of this dose in the general population. effects resembled less then 0.5mg of Xanax. I could only find on other report of this combination from u/ VioletFyah. Another 1g was taken the next morning with mild effects as well.

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1 year ago