In the words of the Colombian president Ivan Duque who made the announcement on 14 January 2019, PROSUR would be "a South American coordination mechanism for public policies, in defense of democracy, the independence of powers, the market economy, the social agenda, with sustainability and with due application". On 18 February 2019, the President of Chile, Sebastián Piñera, said "this new forum will be open to all South American countries that meet two requirements: full validity of the rule of law and full respect for freedoms and human rights".

While PROSUL has been characterized as a right wing version of UNASUL, a similar South American political and economic integration project spearheaded by the Venezuelan government. The right wing nature of the agreement alienated several moderate countries in South America like Uruguay, Guyana, Suriname and socialist nations like Bolivia. Combined with the fact that the original governments that signed the declaration that founded PROSUL are under threat from backsliding into leftist governments that would rather rejoin UNASUL than to continue the integration project. The divisive nature of UNASUL and PROSUL has made historians and politicians in south America call the new relationship a “mini cold war” between the Bolivarian bloc and the Conservative bloc that will only make integration harder, not easier.

The new governments of Pedro Castillo in Peru, Alberto Fernandez in Argentina and the MAS victory in Bolivia even after Añez’s coup in 2019 heralded the potential beggining of a second Pink wave in the continent. The Itamary in order to quell fears of a confrontational nature of PROSUL to the Venezuelans, called for a new declaration where “South America is a continent of diversity, which includes political affiliations. Rather than divide ourselves by petty politics, we must unite primarily on the condition of democratization and human rights with the establishment of free markets second to the state.” The declaration was seen less of an ideological motivation to keep PROSUL as a reactionary organization and more as a consolidation of PROSUL’s legitimacy and acknowledging the plurality of PROSUL’s composition. The hope is that through reforms of PROSUL towards a more moderate plural organization would help to further consolidate and invite non aligned south american nations into the bloc.

Uruguay, the Guyanas and Bolivia are invited into PROSUL as a result with a moderate reform of PROSUL.