It seems obvious that Tippett will look to shake up the lines for next game. Maybe not full on blender, but tweaks to give a jump. We saw a few last game, with Puljujarvi and Yamamoto swapping spots. Here's what I could imagine seeing next game:

93 - 97 - 56
Nuge and Yams play off each other well, and McDavid is McDavid. Yams provides a lot of energy, and this line could wreak havoc.

63 - 29 - 13
Draisaitl is looking like he's a little banged up, so giving him a bigger body on his wing might allow him to stay out of the tough corners. Ennis has been playing well, and plays a lot like Yamamoto.

21 - 91 - 18
If Chiasson gets suspended, Neal likely draws back in.

10 - 16 - 15
Nygard has to get in a game sometime, right? His speed, with Khaira and Archibald doing their thing, this could be an effective line.

For the defence, I have no idea. I feel like we had our best possible pairings last night. Rookie mistakes by Bouchard might mean he is out of the lineup next game, so Russell is in, unless Lagesson is back.