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Gabapentin cross tolerance with Lyrica?
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So, I‘ve taken Lyrica before. 600mg for the first time, and have taken up to 1200mg before with breaks in between.

After a long break, I was able to get my hands on both lyrica and pregabalin. I took Lyrica the past 2 days (600mg on Day 1, 750-900mg on Day 2 which was yesterday).

I didn’t want to take Lyrica today so I opted for Gabapentin for my first time. I took 400mg on my first dose, and staggered doses up to 1600mg now with my last dose. Had a slice of cheddar with every dose to aid with absorption.

I don’t feel anything at all. Is this normal? Or did I build a tolerance two days before with the Lyrica?

I read somewhere that Lyrica has a cross-tolerance with Gabapentin but not the other way around. I’m not sure if this is true.

Any help would be appreciated. Cheers.

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1 day ago