I suffer from ADHD and CFS, and have tried various medications, but methylphenidate has no effect at all. (Rather, it worsens my hyperactivity and stereotyped behavior, and reduces my work ability.)

So I tried Atomoxetine, but it only caused side effects and had no effect.

However, my ADHD improves significantly when I take drugs that increase noradrenaline, so I tried Nortriptyline (tricyclic antidepressants), and my task processing ability improved significantly. However, it significantly extends my QT, so I cannot use it for long.

Also, I have a strange constitution and react sensitively (or badly) to many drugs that involve cyp2d6, but Cymbalta did not cause any side effects at all.

(However, Cymbalta became completely ineffective after the first two months.)

In this case, are there any recommended drugs to improve my ADHD?

I would be happy if you could suggest something, even if it is an unconventional method or a drug that is beyond my imagination.

My life is a mess because of ADHD (and technically CFS).

*Medications I've tried in the past

Methylphenidate, Abilify, bupropion → I had the same bad reaction

Nortriptyline, Imipramine → Improved ADHD

Cymbalta, milnacipran, Desvenlafaxine → Only helped for the first few months

Also, I feel like antipsychotics like Blonanserin might help my ADHD, but am I overthinking it?

Clonazepam and Lamotrigine help my ADHD a little,

which is strange because dopamine makes my ADHD much worse anyway.