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The article “Intranasal delivery of gabapentin optimized for augmented permeation”
Gave me the idea for a simple method to enhance oral bioavailability
Their formulation was essentially (simplified )
MCT oil, Polysorbate 80, often used in foods and cosmetics and polyethylene glycol a sweetener used in vape juice)
Blended for an hour or two
Even more simply you could simply blend gabapentin with MCT oil
comprising of generally regarded as a safe (GRAS) category lipid, surfactant (tween 80) and co-surfactant (polyethylene glycol 400) [10,11].
https://doi.org/10.1016/j.jddst.2020.101606
https://www.sciencedirect.com/science/article/pii/S1773224719320064?via=ihub
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