https://www.sciencedirect.com/science/article/pii/S2707368824000566

• Apigenin, a flavonoid in fruits and veggies, shows promise as a chemopreventive agent in cancer therapy. • It induces apoptosis, inhibits angiogenesis, and suppresses metastasis in cancer cells. • Review highlights apigenin's therapeutic promise and calls for more research in targeted cancer chemotherapy.

1. Conclusion Finally, apigenin appears to be a promising natural chemical with significant possibilities for cancer therapy. Its various pharmacological features, such as apoptosis induction, angiogenesis inhibition, and metastasis suppression, make it a promising candidate for targeted cancer treatment. Furthermore, its synergistic interactions with traditional chemotherapeutic drugs and potential as an adjuvant therapy provide new paths for improving therapeutic outcomes. Furthermore, new advances in nanoparticle-based delivery systems show promise for addressing the obstacles associated with apigenin's low bioavailability and stability, hence enhancing its efficacy in cancer prevention and treatment. These advancements mark a significant step towards realizing apigenin's maximum effectiveness in targeted chemotherapeutics. In summary, the complete examination of apigenin's phytochemical properties, pharmacological activity, and improvements in delivery systems given in this study highlights its importance as a significant tool in the fight against cancer. More research and clinical trials are needed to evaluate its efficacy, optimize treatment techniques, and ultimately enhance outcomes for patients in cancer therapy.

Other neurochemical benefits: https://docs.google.com/document/d/1UmEiMo0TqITjZM7GRcLgmWsBffl4Oqqex3dgJW0G7aA/edit?usp=sharing

My impressions:

I started taking 50mg Liposomal Apigenin first before sleep, now I take it in morning as apigenin is D2 agonist and weak reversable MAO-A so for my neurochemistry is best if I take it in morning or afternoon, before sleep I react greatly on Tauromag(Magnesium acetyl Taurinate).

I think 50mg plain apigenin would be good one hour before sleep but 50mg liposomal apigenin is like taking 200mg plain apigenin(so here is the catch in dosage wise).

I have problems all my life with excess glutamate and this works like charm for GAD67. Better than agmatine or emoxypine in my experience.

It inhibit reactivation of many retro viruses(ebv, hhv6 etc). That's probably why totally stopped my neuroinflammation and varoius neurological symptoms. Only with TTFD and R-lipoic acid I was having some succes for polyneuropathy.

I'm HIGHLY impressed with this compound. Many uses it in anti-aging protocol(boost indirectly NAD through CD38 inhibition)but it's much much more and has long half life.