Small AVD setup with 6 users. It's fairly new and still in a somewhat testing phase so far with fslogix. They do not use any apps other than MS Office and Edge. I notice every Sunday that my Azure backup report at 8AM doesn't show my Azure VMs at all. I connect via remote desktop app and open outlook, can't connect to M365. Customer complains that they can't open certain things over the web from within Office apps like Access or Excel. I connect to the VM directly through a third party access solution (screenconnect) and the VM is laggy and never presents me with a login or a desktop. I do not see anything odd in the event logs. Web pages seem to load fine, I thought it might be exhausting NAT but that doesn't seem to be the case either. If I reboot, it returns to normal, lasts about a week, then same thing again. Azure backup has been working fine with two other VMs for quite a while now. I am also backing up the fslogix profiles that are in Azure storage. Any thoughts?

Edit:

VM SKU is a Standard_D8ls_V5 - 8 Core 16GB

Image is the multi session W11 23H2