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In your experience, what dosage of Risperidone is most effective to augment an AD for unipolar depression?
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My psychiatrist started me on 0.5mg added to 20mg Trintellix and I noticed an improvement within 1 week but now 3 weeks in, I’m still having bothersome depressive symptoms. I see her next week and I’m assuming we’ll go to 1mg/day. She wanted to try 0.5mg for 4 weeks. I have virtually no side effects.

I know that a lower dose is typically used for augmentation for depression. But in your experience, what do you find the most effective dose to be? Am I considered to be on a sub-therapeutic dose at 0.5mg/day? Can bumping the dose just by a little bit really help?

Thank you!

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4 months ago