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These are the symptoms most important for *actual* function. And this is even discussed in this video by a researcher/specialist on anhedonia:
https://www.youtube.com/watch?v=oMfOUlKBlFw
Most of the scores on things like PHQ9 and MADRS are meaningless, and the doc mentions how he was taught that all symptoms are equal, as these scales weight it equally. But that is not actually the case. And things like CBT do not work well for anhedonia/cognition. Many ADs also numb emotion. The symptoms also make people hopeless and desperate to the point many go looking for research chemicals. There is also complex gut-brain-immune axis disruptions in many anhedonia cases it is create by inflammation or dysbiosis, yet conventional medicine has no way to actually target this and probably won't for years
Many antidepressants are also currently failing since placebo effect is so high. And anhedonic patients or patients with cognitive issues are not separated from the low mood/sadness patients and essentially this creates a problem. Low mood responds a lot better to placebo than anhedonia, which itself suppresses the opiod system involved in placebo response. So its illogical to have all patients in the same trial. And things like CBT have been overstated as helpful.
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