I am a gay man who engages in anal sex and I have had a chronic fissure for about 7 years now. Last year I started taking roughly 2.5mg/5mg Tadalafil every other day but now most days because I wanted tougher erections and also found it’s good for general penis health. After a few weeks I noticed that I completely stopped bleeding when having a bowel movement. Before this, although I had been taking fibre and drinking lots of water for a while, this has helped but even the slightest large BM would cause a re-tear.

I also noticed that when receiving anal sex, it felt crazily easier for the penis to enter and I wouldn’t have to tap out because of the pain. I was so confused as to why this was happening but then realised I had just started taking Tadalafil.

It’s been 5 months now and I haven’t had a single re-tear. This is definitely the longest time I’ve gone without it reopening. I’ve also had a lot of sex and larger BMs in this time, but still upping my fibre and water intake.

I also found this study which confirmed my results. This study talks about Sildenafil which is viagra but both Sildenafil and Tadalafil are PDE5 inhibitors. Tadalafil is just a much lighter version and lasts in the body longer which is great!

https://pubmed.ncbi.nlm.nih.gov/17335124/

PSA men who engage in anal sex or use poppers for whatever reason, DO NOT use poppers with this drug it is extremely dangerous!

Sorry women Tadalafil/Cialis is for men only. I’m not sure of the effects it had on women.

Hope this helps! :)

Edit: At the bottom of the linked study above, it states this - “Conclusion: Sildenafil relaxes the augmented tone of human IAS in vitro. These results support the potential use of this PDE5 inhibitor in the treatment of chronic anal fissure.”