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Methylphenidate and nicotine
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Hi there,

Can nicotine impact the effectiveness of methylphenidate? I researched online but couldn’t really find anything to suggest it does. A Reddit post on this sub about 3 years ago said that it does impact it in a negative way by basically canceling it out.

I’ve been struggling to see any benefit since upping my methylphenidate to 54mg and I was wondering if that could be a reason why? I would vape quite a lot so I could definitely see it having a bad interaction.

Thanks 🙏

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12 hours ago