Just curious if anyone else experienced horrible head splitting headaches while using this supplement. I started taking it as an alternative to cymbalta, the side effects of pretty much any antidepressant I’ve tried include shivering, diarrhea, hand and body shaking, nausea and vomiting. Since weening myself off of pharmaceuticals and starting 5-htp I’ve noticed a huge difference in my mood, works better than any antidepressant ever did for me. But I’m beginning to get discouraged as I think my headache might be from taking this supplement. I take 200mg time release tablet in the morning on an empty stomach with a multivitamin.

I’ve read that it can cause leaky heart syndrome but that study was conducted only using mice and giving them an extremely high dose of it, so I’m not really concerned about that.

Can smoking and eating cannabis have an impact on my serotonin levels?