Curious about how 2cb cross tolerance works with LSD. Yesterday I tripped hard on 25mg’s orally of 2cb, visuals were comparable to 150 ug’s of acid with a nice headspace and very little nausea because I used ginger pills. This is the highest oral dose I’ve personally taken.

My girlfriend took the same dosage and got zero visuals and barely any headspace only extreme nausea. She has done a LOT of psychedelics specifically LSD about 6-7 years ago and was at one point dropping 600 ug’s frequently like it was nothing. We use our 2cb nasal spray a lot and she gets super light effects and only got light visuals one time when we reached around 15mg’s nasally done over the course of about 4 hours. I was getting major visuals at this point and she only got light amounts of visual movementz

Shes not on SSRI’s or any other medications, but 2cb specifically is extremely mild for her consistently. Could she still have a tolerance after that long since doing a lot of LSD/a good amount of other substances? We thought it seemed too long of a timeframe but it seems like the only answer.

We’ll be trying to get her to have a full trip on 2cb again by upping her dosage to 30mg’s oral and having me sober trip sit.