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If there was one paper, compound [family] or synthesis route you wish would catch on within the clandestine pharmacology community which would it be?
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For me it'd probably be cocaine analogues. The literature is shockingly dense and the demand and social costs of the trade are both astronomical.
I recently started listening to the Spice episode and it feels like a similar instance of "oh but who's the audience for that" type cultural hesitancy not really backed up by anything else.
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The helional thing seems anecdotally be running already, actually. Lots of pills turning up as MDA with implications of identifying contaminations lately.
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That is a strong fucking contender oh my god 👀👀👀👀
Opiate availability and cleanness is such a horrifically messy topic.