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This is my annual reminder that the NHS website (UK health service) still publishes a document that says that excess estrogen is de-aromatized back to testosterone in transgender women, an enzyme (dearomatase) that humans literally do not have.
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Drwillpowers is in Delaware
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Was talking to another clinician and mentioned this, and I went to check and see if they had yet fixed it. I've publicly called it out for 3 years now.

Nah. Still there.

https://remedy.bnssgccg.nhs.uk/media/3304/hormonal-treatment-london-clinic-mtf-2011.pdf

https://gendercare.co.uk/leighton-seal.shtml

"Using excessive amounts of oestrogen does not improve breast development, indeed there is an enzyme present in the body that converts excess oestrogen back into testosterone and so this may be counterproductive."  

If you aren't versed in transition biochemistry, this is a false statement. Testosterone is converted to estradiol via the enzyme aromatase. Its a one way bridge, no goesies-backsies. Humans do not have a de-aromatase enzyme. I can inject a human with bottles upon bottles of E2 and their T will not rise as a result.

This example is ALMOST as bad as University of Michigan putting out their Anti-bicalutamide document, authored by Dr. Randolph, stating how dangerous Bicalutamide was. The same Dr. Randolph that put out his own publication two years earlier talking about how Bicalutamide was a good alternative option for MTF patients. If you want to see that clownery, here:

https://www.reddit.com/r/DrWillPowers/comments/m7aw9c/university_of_michigan_put_out_a_document_which/

These are the people that call me a quack. Admittedly, I'm sort of reaching the point where I think I'm going to just start going to the WPATH and other conferences and trying to explain the biochemistry behind why my stuff works as it is just readily apparent that the issue in a lot of countries is a literal lack of knowledge of the basic biochemistry of transition and human sex hormones. The "trusted endocrinologists" who are leaders in these countries have examples in PRINT of completely wrong things in regards to the biochem. I can't convince people of an alternative way of doing things who don't even understand the original way of doing it that they currently do. I honestly don't really care anymore what they call me. Some docs out there are listening and if I can change a few minds that's better than none.

Apparently I was a discussion topic at the WPATH this year, and people were annoyed about being asked about my methods all the time by patients, but at the same time, were curious about some of the things (like putting topical T on an atrophied penis or neovagina rather than E, the standard treatment). A few clinicians apparently spoke out on behalf of things I do that they have adopted and the good results they got, and there was some amount of support there. So maybe I can finally go to one of these things without being called every name in the book and people will hear me out. Stay tuned on that. It sounds like this year for the first year, the tides are starting to turn and people are recognizing that maybe there is a reason why so many people support my method of doing things.

Also, please stop going to your doctors and requesting "The Powers Method". This literally just angers them. Go request rectal progesterone, topical low dose T, intermittent oral dosing, bicalutamide, pellets, whatever. But don't use my name it will only cause you more issues as these doctors don't want to read a 200 page PowerPoint to treat their 3 trans patients 99% of the time. Make your case for the one thing you want, and all the citations needed to justify it are in my ppts. You don't need to say my name and I'd rather you not.

PS: MAYBE THE GUY WHO HAS HAD FOUR GUINNESS WORLD RECORD CATS KNOWS SOMETHING ABOUT MAMMALIAN BIOCHEMISTRY? Nah, just a coincidence....he a quack yo.

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2 years ago